Hiding in Plain Sight: A Consideration of NF1-Associated Hypovitaminosis D and its Treatment

摘要: This article deals with the autosomal dominant human genetic disorder, Neurofibromatosis Type 1 (NF1), and has three main foci. The first is general principle that substantial advances in understanding pathogenesis of a disorder can derive from timely reconsideration material previously overlooked or otherwise not given its due. There are times when key to supposed “mystery” hiding plain sight. second focus specific consideration selected elements an apparent vitamin D deficiency NF1. And third this reconsiders mast cell NF1 pathogenesis, including potential being “mastocytosis” sorts, prospect additional grounds for treatment blockers, example, ketotifen.