The prognostic significance of blood pressure in the elderly.

摘要: Whilst recruiting for the Randomised Trial of Treatment Hypertension in Elderly Patients Primary Care, 10,732 people aged 60-79 years age (4,736 males and 5,996 females) were screened hypertension. This constituted 78% those eligible on practice lists this range. These patients followed up a mean period 2.6 (range 0.1-11.2 years). All leaving practices registered with National Health Service Central Registry to ensure completeness death ascertainment. 1,009 deaths analysed standardised mortality ratios computed all deaths, stroke, coronary artery disease cardiovascular causes. Hypertensive included control group trial also matched found be normotensive their mortalities compared. Both high low levels SBP associated increased producing U-shaped curve J-shaped curves With increasing higher lower became more pronounced. Similar effects evident DBP but women was less dangerous than men. Although relative impact hypertension declines advancing age, absolute is maintained eighty.