J-Curve Phenomenon: Does It Exist?
作者： Sripal Bangalore , Franz H. Messerli
DOI: 10.1007/978-88-470-2601-8_23
关键词:
摘要: Numerous studies over the past few years have documented an non-linear relationship between blood pressure and cardiovascular events (i.e., a J-shaped curve), especially in patients with known coronary artery disease. In most of these though J-curve was seen, there shallow part for systolic range 110–140 mm Hg diastolic pressures 70–90 Hg, below above which risk outcomes increased exponentially. Although this has been extensively debated, possibility confounders cannot be completely ruled out. This can only addressed randomized trial powered to test association. Regardless whether exists within physiological BP, is no evidence date suggest that aggressive BP control lower than 130–140 beneficial (except stroke) but associated increase serious adverse effects including hypotension. It would prudent, though, healthcare providers set targets judiciously select patient populations considering underlying pathophysiology individual cerebrovascular
springer.com
sci-hub.se 参考文章(60)
World Health Organization, International Society of Hypertension Writing Group, None, 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. Journal of Hypertension. ,vol. 21, pp. 1983- 1992 ,(2003) , 10.1097/00004872-200311000-00002
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. The Lancet. ,vol. 360, pp. 1903- 1913 ,(2002) , 10.1016/S0140-6736(02)11911-8
Coope J, McPherson K, Warrender Ts, The prognostic significance of blood pressure in the elderly. Journal of Human Hypertension. ,vol. 2, pp. 79- 88 ,(1988)
, Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials The Lancet. ,vol. 362, pp. 1527- 1535 ,(2003) , 10.1016/S0140-6736(03)14739-3
Lisa E. Farnett, The J-Curve Phenomenon and the Treatment of Hypertension-Reply JAMA: The Journal of the American Medical Association. ,vol. 266, pp. 65- 66 ,(1991) , 10.1001/JAMA.1991.03470010068027
JohnM. Cruickshank, JeffreyM. Thorp, F.James Zacharias, BENEFITS AND POTENTIAL HARM OF LOWERING HIGH BLOOD PRESSURE The Lancet. ,vol. 329, pp. 581- 584 ,(1987) , 10.1016/S0140-6736(87)90231-5
Athanase Benetos, Frederique Thomas, Michel E Safar, Kathryn E Bean, Louis Guize, Should diastolic and systolic blood pressure be considered for cardiovascular risk evaluation: a study in middle-aged men and women Journal of the American College of Cardiology. ,vol. 37, pp. 163- 168 ,(2001) , 10.1016/S0735-1097(00)01092-5
ALBERT R. JONSEN, Do No Harm Annals of Internal Medicine. ,vol. 88, pp. 827- 832 ,(1978) , 10.7326/0003-4819-88-6-827
Sripal Bangalore, Jie Qin, Sarah Sloan, Sabina A. Murphy, Christopher P. Cannon, , What Is the Optimal Blood Pressure in Patients After Acute Coronary Syndromes? Relationship of Blood Pressure and Cardiovascular Events in the Pravastatin or Atorvastatin Evaluation and Infection Therapy–Thrombolysis in Myocardial Infarction (PROVE IT-TIMI) 22 Trial Circulation. ,vol. 122, pp. 2142- 2151 ,(2010) , 10.1161/CIRCULATIONAHA.109.905687
M. Viigimaa, B. Waeber, B. Williams, J. L. Zamorano, , , , , G. Mancia, G. De Backer, A. Dominiczak, R. Cifkova, R. Fagard, G. Germano, G. Grassi, A. M. Heagerty, S. E. Kjeldsen, S. Laurent, K. Narkiewicz, L. Ruilope, A. Rynkiewicz, R. E. Schmieder, H. A.J. Struijker Boudier, A. Zanchetti, A. Vahanian, J. Camm, R. De Caterina, V. Dean, K. Dickstein, G. Filippatos, C. Funck-Brentano, I. Hellemans, S. D. Kristensen, K. McGregor, U. Sechtem, S. Silber, M. Tendera, P. Widimsky, J. L. Zamorano, S. E. Kjeldsen, S. Erdine, K. Narkiewicz, W. Kiowski, E. Agabiti-Rosei, E. Ambrosioni, R. Cifkova, A. Dominiczak, R. Fagard, A. M. Heagerty, S. Laurent, L. H. Lindholm, G. Mancia, A. Manolis, P. M. Nilsson, J. Redon, R. E. Schmieder, H. A.J. Struijker-Boudier, M. Viigimaa, G. Filippatos, S. Adamopoulos, E. Agabiti-Rosei, E. Ambrosioni, V. Bertomeu, D. Clement, S. Erdine, C. Farsang, D. Gaita, W. Kiowski, G. Lip, J.-M. Mallion, A. J. Manolis, P. M. Nilsson, E. O'Brien, P. Ponikowski, J. Redon, F. Ruschitzka, J. Tamargo, P. van Zwieten, 2007 Guidelines for the management of arterial hypertension European Heart Journal. ,vol. 28, pp. 1462- 1536 ,(2007) , 10.1093/EURHEARTJ/EHM236