Diabetes is associated with increased risks of low lean mass and slow gait speed when peripheral artery disease is present.

作者: Ching-Lung Cheung , Karen S.L. Lam , Bernard M.Y. Cheung

DOI: 10.1016/J.JDIACOMP.2015.11.015

关键词: MedicineNational Health and Nutrition Examination SurveyPopulationBody mass indexDiabetes mellitusPreferred walking speedGaitPhysical therapyCross-sectional studyLean body mass

摘要: Abstract Aims The aim of the current study was to evaluate independent relationship diabetes and PAD with lean mass gait speed. Methods This a cross-sectional U.S. population in 1999 through 2004, including 4769 participants aged ≥40years National Health Nutrition Examination Survey 1999–2004. Appendicular divided by body index (ALM BMI ) speed were analyzed. Low defined as ALM Results In fully adjusted model, both had higher odds low (OR=2.21; 95% CI: 1.07–4.57) mobility impairment (OR=4.8; 1.93–11.97) when compared neither nor PAD. No significant association "with without PAD" or diabetes" observed. Participants significantly lower all other participants. Conclusions People likelihood impairment; such not observed people either alone.

参考文章(37)
Ching-Lung Cheung, Uyen-Sa D. T. Nguyen, Eleanor Au, Kathryn C. B. Tan, Annie W. C. Kung, Association of handgrip strength with chronic diseases and multimorbidity: A cross-sectional study Age. ,vol. 35, pp. 929- 941 ,(2013) , 10.1007/S11357-012-9385-Y
Timur Selcuk Akpinar, Mehmet Tayfur, Fatih Tufan, Türker Şahinkaya, Murat Köse, Ekmel Burak Özşenel, Gülistan Bahat Öztürk, Bülent Saka, Nilgün Erten, Safinaz Yildiz, Mehmet Akif Karan, Uncomplicated diabetes does not accelerate age-related sarcopenia The Aging Male. ,vol. 17, pp. 205- 210 ,(2014) , 10.3109/13685538.2014.963040
D. E. Kelley, J. He, E. V. Menshikova, V. B. Ritov, Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes Diabetes. ,vol. 51, pp. 2944- 2950 ,(2002) , 10.2337/DIABETES.51.10.2944
Andrew S. Levey, Lesley A. Stevens, Christopher H. Schmid, Yaping (Lucy) Zhang, Alejandro F. Castro, Harold I. Feldman, John W. Kusek, Paul Eggers, Frederick Van Lente, Tom Greene, Josef Coresh, , A New Equation to Estimate Glomerular Filtration Rate Annals of Internal Medicine. ,vol. 150, pp. 604- 612 ,(2009) , 10.7326/0003-4819-150-9-200905050-00006
Stephanie A. Studenski, Katherine W. Peters, Dawn E. Alley, Peggy M. Cawthon, Robert R. McLean, Tamara B. Harris, Luigi Ferrucci, Jack M. Guralnik, Maren S. Fragala, Anne M. Kenny, Douglas P. Kiel, Stephen B. Kritchevsky, Michelle D. Shardell, Thuy-Tien L. Dam, Maria T. Vassileva, The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates Journals of Gerontology Series A-biological Sciences and Medical Sciences. ,vol. 69, pp. 547- 558 ,(2014) , 10.1093/GERONA/GLU010
S. Volpato, L. Bianchi, F. Lauretani, F. Lauretani, S. Bandinelli, J. M. Guralnik, G. Zuliani, L. Ferrucci, Role of Muscle Mass and Muscle Quality in the Association Between Diabetes and Gait Speed Diabetes Care. ,vol. 35, pp. 1672- 1679 ,(2012) , 10.2337/DC11-2202
Ching-Lung Cheung, Karen S. L. Lam, Bernard M. Y. Cheung, Evaluation of Cutpoints for Low Lean Mass and Slow Gait Speed in Predicting Death in the National Health and Nutrition Examination Survey 1999–2004 Journals of Gerontology Series A-biological Sciences and Medical Sciences. ,vol. 71, pp. 90- 95 ,(2016) , 10.1093/GERONA/GLV112
Justin D. Anderson, Frederick H. Epstein, Craig H. Meyer, Klaus D. Hagspiel, Hongkun Wang, Stuart S. Berr, Nancy L. Harthun, Arthur Weltman, Joseph M. DiMaria, Amy M. West, Christopher M. Kramer, Multifactorial Determinants of Functional Capacity in Peripheral Arterial Disease: Uncoupling of Calf Muscle Perfusion and Metabolism Journal of the American College of Cardiology. ,vol. 54, pp. 628- 635 ,(2009) , 10.1016/J.JACC.2009.01.080
Mary M. McDermott, Frederick Hoff, Luigi Ferrucci, William H. Pearce, Jack M. Guralnik, Lu Tian, Kiang Liu, Joseph R. Schneider, Leena Sharma, Jin Tan, Michael H. Criqui, Lower extremity ischemia, calf skeletal muscle characteristics, and functional impairment in peripheral arterial disease Journal of the American Geriatrics Society. ,vol. 55, pp. 400- 406 ,(2007) , 10.1111/J.1532-5415.2007.01092.X
Kyung-Soo Kim, Kyung-Sun Park, Moon-Jong Kim, Soo-Kyung Kim, Yong-Wook Cho, Seok Won Park, Type 2 diabetes is associated with low muscle mass in older adults. Geriatrics & Gerontology International. ,vol. 14, pp. 115- 121 ,(2014) , 10.1111/GGI.12189