Evaluation of Cutpoints for Low Lean Mass and Slow Gait Speed in Predicting Death in the National Health and Nutrition Examination Survey 1999–2004
作者： Ching-Lung Cheung , Karen S. L. Lam , Bernard M. Y. Cheung
关键词: Sarcopenia 、 Demography 、 Gerontology 、 Medicine 、 Gait 、 Proportional hazards model 、 National Health and Nutrition Examination Survey 、 Hazard ratio 、 Body mass index 、 Lean body mass 、 Preferred walking speed
摘要: BACKGROUND Sarcopenia is commonly defined as loss of muscle mass with limited function or strength. Different cutpoints low lean and slow gait speed have been proposed by different professional working groups. We compared the performance in predicting death. METHODS analyzed data participants aged 65 years older from continuous National Health Nutrition Examination Survey 1999-2004 (N = 2,841), subsequent follow-up on mortality up to December 31, 2006. For mass, based appendicular (ALM) alone, ALM adjusted for body index (ALMBMI), height squared (ALMH2) were evaluated. speed, 0.8 1.0 m/s A Cox-proportional hazard regression model adjustment multiple confounding factors was used association analyses. RESULTS ALMBMI (<0.512 women <0.789 men) showed most significant highest ratio death (hazard 1.72; 95% CI: 1.28-2.29). all tested full (p < .001), while cutpoint (2.32; 1.58-3.39). CONCLUSIONS Low strongest death; death, being observed m/s. Further studies validating are warranted before using them clinical settings.
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