Visualisation of presence, location, and transmural extent of healed Q-wave and non-Q-wave myocardial infarction.

作者: Edwin Wu , Robert M Judd , John D Vargas , Francis J Klocke , Robert O Bonow

DOI: 10.1016/S0140-6736(00)03567-4

关键词: Creatine kinaseNuclear medicineMagnetic resonance imagingCardiologyElectrocardiographyAngiographyInternal medicineMyocardial infarctionInfarctionMedicineCardiomyopathyEndocardium

摘要: Summary Background A technical advance in contrast-enhanced magnetic resonance imaging (MRI) has significantly improved image quality. We investigated whether healed myocardial infarction can be visualised as hyperenhanced regions with this new technique, and assessment of the transmural extent yields physiological data. Methods 82 MRI examinations were carried out three groups: patients infarction; non-ischaemic cardiomyopathy; healthy volunteers. Patients prospectively enrolled after enyzmatically proven necrosis imaged 3 months (SD 1) or 14 (7) later. The procedure used a segmented inversion-recovery gradient-echo sequence gadolinium administration. Findings compared those coronary angiography, electrocardiography, cine MRI, creatine kinase measurements. 29 (91%) 32 infarcts at (13 non-Q-wave) all 19 (eight showed hyperenhancement. In whom infarct-related-artery was identified by 24 25 had hyperenhancement appropriate territory. None 20 non ischaemic cardiomyopathy 11 volunteers Irrespective presence absence Q waves, majority only non-transmural involvement. Normal left-ventricular contraction shown seven examined months, but these cases limited to subendocardium. Interpretation presence, location, Q-wave non-Q-wave accurately determined contrastenhanced MRI.

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