Sudden unexpected death in epilepsy: basic mechanisms and clinical implications for prevention
作者： Brian J Dlouhy , Brian K Gehlbach , George B Richerson
关键词: In patient 、 Psychiatry 、 Sudden death 、 Unexpected death 、 Population 、 Lifetime risk 、 Epilepsy 、 Intractable epilepsy 、 Medicine 、 Epilepsy surgery
摘要: Sudden unexpected death in epilepsy (SUDEP) is the most common cause of patients with intractable epilepsy. The substantial lifetime risk SUDEP and lack a clear pathophysiological connection between itself sudden have fuelled increased attention to this phenomenon. Understanding mechanisms underlying paramount developing preventative strategies. In review, we discuss population studies, case-control witnessed monitored cases, as well human seizure cardiorespiratory findings related SUDEP, animal models. We integrate these data suggest probable SUDEP. modifiable factors pathophysiology allows us potential
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