Apnoea and bradycardia during epileptic seizures: relation to sudden death in epilepsy.

作者: L Nashef , F Walker , P Allen , J W Sander , S D Shorvon

DOI: 10.1136/JNNP.60.3.297

关键词:

摘要: OBJECTIVE--To record non-invasively ictal cardiorespiratory variables. METHODS--Techniques employed in polysomnography were used patients with epilepsy undergoing EEG-video recording at a telemetry unit. RESULTS--Apnoea (> 10, range > 10-63, mean 24 s) was seen 20 of 47 clinical seizures (three secondary generalised, 16 complex partial, and one tonic) 10 17 patients. Apnoea central patients, but obstructive apnoea also recorded three 10. Oxyhaemoglobin saturation (SpO2) dropped to less than 85% (six patients). An increase heart rate common (91% seizures). Bradycardia/sinus arrest documented four (mean maximum RR interval 5.36, 2.8-8.6 always the context change respiratory pattern. CONCLUSION--Ictal often seen. The occurrence bradycardia association suggests involvement reflexes. Similar mechanisms may operate cases sudden death epilepsy.

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