Correlation of coronary calcification and angiographically documented stenoses in patients with suspected coronary artery disease: results of 1,764 patients

摘要: OBJECTIVES This study correlated the electron beam computed tomographic (EBCT) calcium scores with results of coronary angiography in symptomatic patients order to assess its value predict or exclude significant artery disease (CAD). BACKGROUND Electron tomography is a sensitive method detect calcium. However, it unclear whether may play role as filter before invasive procedures patients. METHODS A total 1,764 (1,225 men and 539 women) suspected CAD from single center were included our study. All underwent screening EBCT (C150XP Imatron) conventional angiography. RESULTS Fifty-six percent 47% women revealed stenoses (≥50%). Total exclusion (14% group) was associated an extremely low probability stenosis (<1%). With ≥20th, ≥100th ≥75th percentile age groups, sensitivity decreased 97%, 93% 81%, respectively, 98%, 82% 76%, women. At same time, specificity increased up 77% There difference between all groups; however, receiver-operating characteristic curves indicated that test can be performed equal accuracy these subgroups. CONCLUSIONS Calcium highly moderately specific stenotic disease. Exclusion defines substantial subgroup patients, albeit symptomatic, very stenoses.