Advances in the Treatment of Malignant Gliomas

摘要: Local control with surgery, radiation, and temozolomide chemotherapy remain the pillars of treatment for high-grade gliomas. Novel therapeutic strategies, including a variety antiangiogenic agents, are under investigation. One these bevacizumab, was recently given accelerated approval by US Food Drug Administration as single agent recurrent glioblastoma. Recent trial results generating important clinical questions regarding which patients to treat when, how best monitor response. Encouraging recent studies driving willingness undertake aggressive improve outcomes in this population. In era, better understanding biology, molecular aspects cancer, methodology crucial clinicians. This review focuses on advances malignant gliomas, especially therapy.