Radioimmunoassay of Eicosanoids Associated with Tumor Growth

摘要: Although prostaglandin production has been associated with neoplasia, a causal relationship never demonstrated. Most mammalian cells have the enzymes that metabolize arachidonic acid, hut capacity to generate thromboxanes, prostacyclins, various prostaglandins, mono- and dihydroxyfatty acids peptide-containing leukotrienes from endogenous substrate varies among (1–7). The relative levels of these acid metabolites produced endogenously (the cell’s metabolite profile) also can vary state differentiation nutritional history. Examples how 1) genetic specification (although it should be realized postreplicative events are important), 2) differentiation, 3) nutrition affect profiles given in Table 1, Fig. 1 2, respectively.