Organizational features of the cat and monkey cerebellar nucleocortical projection.

摘要: The organization of the cerebellar nucleocortical projection in cat and monkey has been studied using orthograde retrograde neuroanatomical tracing techniques. Injections tritiated leucine nuclei orthogradely labeled neucleocortical fibers throughout their course to cortex. Their branch points corpus medullare, folial white matter, granular layer were evident from dense, continuous distribution silver grains overlying these axons. results showed that is organized principally into three rostrocaudally oriented longitudinal cortical zones. Fastigial directed medial 1.5–2.5 mm ipsilateral vermis, with a lighter lateral vermis ipsilaterally area contralaterally. interposed projected mainly paravermis-medial hemispheric zone Nucleocortical posterior nucleus paramedian lobule, Crus I lobus simplex, flocculus paraflocculus. projections anterior coursed lobe paravermis ventral folia lobule. A was found edge intermediate areas hemisphere. Dentatocortical II zone, hemisphere along Along periphery each adjacent deep overlapped slightly. transport horseradish peroxidase (HRP) injection sites hemisphere, — paravermis, neurons localized within dentate, interposed, fastigial nuclei, respectively. Retrograde labeling experiments carried out monkeys indicated this species different than cat. In primate, appeared arise dentate nucleus. There secondary input arising This evidence suggests system undergoes significant phylogenetic change its between primate. These organizational differences are discussed light possible functional implicatons.