The impact of joint range of motion limitations on health‐related quality of life in patients with haemophilia A: a prospective study

作者: C.-M. Chen , K.-C. Huang , C.-C. Chen , S.-U. Huang , C.-E. Huang

DOI: 10.1111/HAE.12644

关键词: Haemophilia AProspective cohort studyShouldersHaemophiliaRange of motionPhysical medicine and rehabilitationElbowMedicineQuality of lifePhysical therapySynovitis

摘要: Summary. In patients with haemophilia A, repeated occurrences of haemarthrosis and synovitis lead to limitations in range motion (ROM) major joints. However, the effect joint ROM on health-related quality life (HRQOL) these has not been studied previously. The aim this study was assess impact 10 joints (bilateral shoulders, elbows, hips, knees ankles), combined other possibly influential factors, HRQOL A. 13 movements pain intensity were measured. socio-demographic clinical data recorded. Short-Form 36 used as measurement. Eighteen (mean age: 36.9 years) included. Hip limitations, knee hip predicted physical functioning scale (P < 0.001; adjusted R 2 = 0.553). Shoulder age role limitation due emotional problems 0.373). Elbow severity mental health 0.320). social 0.041; 0.091). Educational level elbow vitality 0.416). hip, knee, shoulder could be predictors for Improving an appropriate treatment strategy enhance patients.

参考文章(31)
M. WALSH, D. MACGREGOR, S. STUCKLESS, B. BARRETT, M. KAWAJA, M.-F. SCULLY, Health-related quality of life in a cohort of adult patients with mild hemophilia A. Journal of Thrombosis and Haemostasis. ,vol. 6, pp. 755- 761 ,(2008) , 10.1111/J.1538-7836.2008.02929.X
M. KHAWAJI, J. ASTERMARK, S. VON MACKENSEN, K. ÅKESSON, E. BERNTORP, Bone density and health-related quality of life in adult patients with severe haemophilia Haemophilia. ,vol. 17, pp. 304- 311 ,(2011) , 10.1111/J.1365-2516.2010.02423.X
Alessandro Gringeri, Lorenzo G. Mantovani, Luciana Scalone, Pier Mannuccio Mannucci, , Cost of care and quality of life for patients with hemophilia complicated by inhibitors: The COCIS study group Blood. ,vol. 102, pp. 2358- 2363 ,(2003) , 10.1182/BLOOD-2003-03-0941
H. K. HARTL, S. REITTER, U. EIDHER, H. RAMSCHAK, C. AY, I. PABINGER, The impact of severe haemophilia on the social status and quality of life among Austrian haemophiliacs Haemophilia. ,vol. 14, pp. 703- 708 ,(2008) , 10.1111/J.1365-2516.2008.01684.X
E. ALPKILIÇ BASKIRT, G. AK, B. ZULFIKAR, Oral and general health-related quality of life among young patients with haemophilia. Haemophilia. ,vol. 15, pp. 193- 198 ,(2009) , 10.1111/J.1365-2516.2008.01919.X
K. Fischer, J. G. Van Der Bom, H. M. Van Den Berg, Health-related quality of life as outcome parameter in haemophilia treatment. Haemophilia. ,vol. 9, pp. 75- 82 ,(2003) , 10.1046/J.1365-2516.9.S1.13.X
A. H. Miners, C. A. Sabin, K. H. Tolley, C. Jenkinson, S. Ebrahim, C. A. Lee, Assessing health-related quality-of-life in patients with severe haemophilia A and B Psychology Health & Medicine. ,vol. 4, pp. 5- 15 ,(1999) , 10.1080/135485099106360
S.-Y. Kim, S.-W. Kim, J.-M. Kim, I.-S. Shin, H.-J. Baek, H.-S. Lee, T.-J. Hwang, J.-S. Yoon, Impact of personality and depression on quality of life in patients with severe haemophilia in Korea. Haemophilia. ,vol. 19, ,(2013) , 10.1111/HAE.12221