Grifolin, a potent antitumour natural product upregulates death-associated protein kinase 1 DAPK1 via p53 in nasopharyngeal carcinoma cells.
作者： Xiang-jian Luo , Li-li Li , Qi-pan Deng , Xin-fang Yu , Li-fang Yang
DOI: 10.1016/J.EJCA.2010.09.021
关键词: Programmed cell death 、 Downregulation and upregulation 、 Biology 、 Tumor suppressor gene 、 Cell 、 Albatrellus confluens 、 Death-Associated Protein Kinase 1 、 Apoptosis 、 Protein kinase A 、 Cancer research
摘要: … by grifolin. We observed that protein as well as mRNA level of DAPK1 was induced by grifolin in a … We found that grifolin increased both Ser392 and Ser20 phosphorylation levels of …
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