Wound Repair

摘要: Abstract Despite rapid progress in our understanding of wound pathobiology, transformative developments the care acute and chronic cutaneous wounds have been elusive. Thus patient quality life remains poor economic burden enormous. Although several natural engineered-skin substitutes are commercially available, many contain tissue cells or cell remnants, which make control difficult, shelf-life under ambient conditions short, user interface less than friendly. Similar problems exist if stem added to wounds. Over past decade, much work has done develop new biomaterials for tissue-engineered skin and/or implantation; however, ability limit inflammation, inhibit injury progression, enhance development a regenerative, rather reparative, scar-forming pathway, obscure. In this chapter normal abnormal pathobiology will be discussed as well some advances engineering substitutes, biomaterials, biology, bioactives regulators healing or, preferably, regeneration.