Drug‐induced cholestasis
作者： Manmeet S. Padda , Mayra Sanchez , Abbasi J. Akhtar , James L. Boyer
DOI: 10.1002/HEP.24229
关键词: Medicine 、 Cholestatic hepatitis 、 Extramural 、 Hepatic drug clearance 、 Cholestasis 、 Bioinformatics 、 Drug induced cholestasis 、 Bile acid 、 Gastroenterology 、 Bile formation 、 Internal medicine 、 Vanishing bile duct syndrome
摘要: Recent progress in understanding the molecular mechanisms of bile formation and cholestasis have led to new insights into pathogenesis drug-induced cholestasis. This review summarizes their variable clinical presentations, examines role transport proteins hepatic drug clearance toxicity, addresses increasing importance genetic determinants, as well practical aspects diagnosis management.
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