Impact of Lifestyle Diseases on Postoperative Complications and Survival in Elderly Patients with Stage I Non-Small Cell Lung Cancer

摘要: Background The influence of lifestyle diseases on postoperative complications and long-term survival in patients with non-small cell lung cancer (NSCLC) is unclear. aim this study was to determine whether were significant risk factors perioperative surgical outcomes elderly stage I NSCLC. Methods Between December 1995 November 2013, 110 aged 65 years or older who underwent resection NSCLC at Dong-A University Hospital retrospectively studied. We assessed the presence following as for mortality: diabetes, hypertension, chronic obstructive pulmonary disease, stroke, ischemic heart disease. Results mean age 71 (range, 82 years). Forty-six (41.8%) had making it most common followed by diabetes (n=23, 20.9%). in-hospital mortality rate 0.9% (n=1). 3-year 5-year rates 78% 64%, respectively. Postoperative developed 32 (29.1%), including 7 (6.4%) prolonged air leakage, 6 (5.5%) atrial fibrillation, 5 (4.5%) delirium atelectasis, 3 (2.7%) acute kidney injury pneumonia. Univariate multivariate analyses showed that a disease only independent factor complications. In analysis, univariate analysis age, smoking, body mass index, extent resection, pathologic associated impaired survival. Multivariate revealed type (hazard ratio [HR], 2.20; 95% confidence interval [CI], 1.08 4.49; p=0.030) (HR, 1.89; CI, 1.02 3.49; p=0.043) adverse impacts Conclusion This demonstrated prognostic complications, but not survival, Therefore, may be influenced