Risk factors for postoperative complications after lung resection for non-small cell lung cancer in elderly patients at a single institution in China.

作者: Guotian Pei , Shijie Zhou , Zhidong Liu , Yi Han , Shaofa Xu

DOI: 10.3978/J.ISSN.2072-1439.2014.07.23

关键词:

摘要: Objective: The purpose of this study was to assess the postoperative complications after lung resection for non-small cell cancer (NSCLC) in elderly patients and identify possible associated risk factors. Methods: All aged 70 years or older who underwent pulmonary NSCLC by either an open approach a thoracoscopic between January 2003 December 2013 at our institution were reviewed. Postoperative events divided into minor major complications. Risk factors assessed univariate multivariate logistic regression analysis. A matched casecontrol performed determine if utilization video-assisted thoracic surgery (VATS) patients’ results decreased compared with thoracotomy. Results: During period, 476 consecutive (410 thoracotomy, 66 thoracoscopy) than NSCLC. occurred 169 (35.5%) overall operative mortality 2.3% (11 patients). Univariate predictors included history smoking (P=0.032), CCI scores ≥3 (P<0.001), pneumonectomy (P=0.016), as well duration (P=0.003). After multiple analysis, [odds ratio (OR) =29.95, P<0.001], (OR =2.26, P=0.029) prolonged (≥180 min) =1.93, P=0.003) remained only independent matching based on age, gender, Charlson Comorbidity Index (CCI), pathologic stage, type resection, there 60 each group. Patients had similar preoperative characteristics. VATS resulted significantly lower rate (25.0% vs. 43.3%, P=0.034) shorter median length stay (19 days, range, 12 35 21 13 38, P=0.013) Conclusions: Pulmonary shows acceptable morbidity mortality. are more likely develop ≥3, those undergo pneumonectomy, surgery. Thoracoscopic minimally invasive is fewer hospital

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