Preparation and characterization of Sr–hardystonite (Sr2ZnSi2O7) for bone repair applications
作者： Meili Zhang , Kaili Lin , Jiang Chang
DOI: 10.1016/J.MSEC.2011.10.017
关键词: Cortical bone 、 Biocompatibility 、 Bone healing 、 Sol-gel 、 Adhesion 、 Flexural strength 、 Materials science 、 Composite material 、 Bone Marrow Stem Cell 、 Hardystonite
摘要: article i nfo In this work, the potential of Sr-hardystonite (Sr2ZnSi2O7) ceramics for biomedical use was first detected. First, pure Sr2ZnSi2O7 powders were successfully synthesized by sol-gel method, and then prepared sintering powder compacts. The mechanical test showed that bending strength Young's modulus could reach 82 MPa 44 GPa, respectively, which close to values human cortical bone. Degradation in Tris-HCl buffer solution had a low degradation rate with less than 3% weight loss after soaking 28 days. Furthermore, vitro biocompatibil- ity evaluated rabbit bone marrow stem cells (rBMSCs) adhesion proliferation assay. results supported proliferation. Taken together, might be candidate preparation implants.
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