Preparation and characterization of Sr-Ti-hardystonite (Sr-Ti-HT) nanocomposite for bone repair application
作者： Saeed Hesaraki , Masoud Hafezi , Mohammad Majid Sepantafar , Hossein Mohammadi
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摘要: Objective(s): Hardystonite (HT) is Zn-modified silicate bioceramics with promising results for bone tissue regeneration. However, HT possesses no obvious apatite formation. Thus, in this study we incorporated Sr and Ti into to prepare Sr-Ti-hardystonite (Sr-Ti-HT) nanocomposite evaluated its vitro bioactivity the purpose of developing a more bioactive substitute material. Materials methods: The Sr-Ti-HT were prepared by mechanical milling subsequent heat treatment. Calcium oxide (CaO), zinc (ZnO) silicon dioxide (SiO2) (all from Merck) mixed molar ratio 2:1:2. mixture powders was then milled planetary ball mill 20 h. In run, ball-to-powder weight 10:1 rotational speed 200 rpm. After synthesis HT, 3% nanotitanium (TiO 2 , Degussa) strontium carbonate (SrCO3, added calcined at 1150°C 6 Simultaneous thermal analysis (STA), X-ray diffraction (XRD), Transmission electron microscopy (TEM) Fourier transform infra-red spectroscopy (FT-IR) performed characterize powders. Results: XRD FT-IR confirmed crystal phase structure TEM images demonstrated nanostructure Further, induced formation showed higher human mesenchymal stem cell (hMSCs) adhesion proliferation compared HT. Conclusion: Our revealed that nanostructured 50 nm, can be activation use as biomaterials orthopedic applications.
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