Hepatoblastoma and hepatocarcinoma in children: analysis of a series of 29 cases.

作者: Frédéric Gauthier , Jacques Valayer , Bao Le Thai , Martine Sinico , Chantal Kalifa

DOI: 10.1016/S0022-3468(86)80513-9

关键词: ComplicationHepatoblastomaChemotherapyAdjunctive treatmentPreoperative embolizationSurgeryFibrolamellar CarcinomaMedicinePreoperative chemotherapy

摘要: Twenty-nine cases of liver malignancies, 26 hepatoblastomas (HB) and 3 hepatocarcinomas (HC), were treated in a 13-year period. All children submitted to operation but four had nonresectable tumors, even after chemotherapy. Surgery the 25 consisted right lobectomy 14, left 9, tumorectomy 2; secondary be performed 5 cases, either because histologic doubt on cut section presumed normal parenchyma, or for local recurrence. Preoperative chemotherapy, instituted routine basis since 1982, did appear facilitate surgery otherwise inoperable tumors. The benefits preoperative embolization, done three children, minimal. Ten died, one immediate postoperative period, eight others from disease, complication Follow-up 18 surviving all recurrence metastasis-free, with alphafetoprotein (AFP) is less than 2 years 11 14. One teen-age girl, fibrolamellar carcinoma has just recently been reoperated later. In spite fact that 6 out 7 operated without adjunctive treatment are cured, systematic course chemotherapy prescribed more recent cases. these yet too short.

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