B(C6F5)3 mediated arene hydrogenation/transannulation of para-methoxyanilines
作者： Lauren E. Longobardi , Tayseer Mahdi , Douglas W. Stephan
DOI: 10.1039/C5DT00921A
关键词: Heptane 、 Ring (chemistry) 、 Methanol 、 Medicinal chemistry 、 Stereochemistry 、 Stoichiometry 、 Chemistry
摘要: The stoichiometric reaction of para-methoxyanilines and B(C6F5)3 under H2 results in reduction the N-bound phenyl ring(s), subsequent transannular ring closure with elimination methanol, affording respective 7-azabicyclo[2.2.1]heptane derivatives.
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