Dietary Supplements and Nutraceuticals under Investigation for COVID-19 Prevention and Treatment

摘要: Coronavirus disease 2019 (COVID-19) has caused global disruption and a significant loss of life. Existing treatments that can be repurposed as prophylactic therapeutic agents may reduce the pandemic's devastation. Emerging evidence potential applications in other contexts led to investigation dietary supplements nutraceuticals for COVID-19. Such products include vitamin C, D, omega 3 polyunsaturated fatty acids, probiotics, zinc, all which are currently under clinical investigation. In this review, we critically appraise surrounding prophylaxis treatment Overall, further study is required before evidence-based recommendations formulated, but nutritional status plays role patient outcomes, these help alleviate deficiencies. For example, indicates D deficiency associated with greater incidence infection severity COVID-19, suggesting supplementation hold or value. A growing number scientific organizations now considering recommending those at high risk Because research preliminary, here evaluate extent nutraceutical COVID-19 crisis.IMPORTANCE Sales have increased during pandemic due their perceived "immune-boosting" effects. However, little known about efficacy against novel coronavirus (severe acute respiratory syndrome 2 [SARS-CoV-2]) it causes, CoV (COVID-19). This review provides critical overview value various from available date. These often by public treating infections supporting immune health. Consumers need aware misinformation false promises some supplements, subject limited regulation authorities. considerably more determine whether exhibit SARS-CoV-2 perspective on involved biological processes relevant recovery prevention