Value of the Bronchodilator Response in Assessing Controller Naïve Asthmatic Children
作者： Stanley P. Galant , Tricia Morphew , Silvia Amaro , Otto Liao
DOI: 10.1016/J.JPEDS.2007.05.004
关键词: Medicine 、 Vital capacity 、 Spirometry 、 Physical therapy 、 Respiratory disease 、 Internal medicine 、 FEV1/FVC ratio 、 Receiver operating characteristic 、 Bronchodilator 、 El Niño 、 Asthma 、 Pediatrics, Perinatology, and Child Health
摘要: Objective To define the bronchodilator response (BDR) cutoff point that best identified asthma to determine frequency of abnormal spirometry results across severity. Study design Controller naive children were evaluated with clinical criteria alone establish a diagnosis and severity classification, then compared BDR, which was calculated as percent change from initial forced expiratory volume in 1 second. Receiver operator characteristic analysis determined for gave combination sensitivity specificity. Results Children (n = 346) 51 without asthma, aged 4 17 years, who met entry identified. The mean BDR asthmatics 8.6% (95% CI, 7.5-9.8), 2.2% 0.2-4.3) non-asthmatics (P Conclusion Spirometric include can potentially identify have clinically mild might benefit controller therapy.
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