Polyethylene glycol-phosphatidylethanolamine (PEG-PE)/vitamin E micelles for co-delivery of paclitaxel and curcumin to overcome multi-drug resistance in ovarian cancer.
作者： Abraham H. Abouzeid , Niravkumar R. Patel , Vladimir P. Torchilin
DOI: 10.1016/J.IJPHARM.2014.01.009
关键词: Chemistry 、 PEG ratio 、 Pharmacology 、 Paclitaxel 、 In vivo 、 Ovarian cancer 、 Polyethylene glycol 、 Cytotoxicity 、 In vitro 、 Curcumin
摘要: … significantly enhance the cytotoxicity of paclitaxel against SK-OV-… advantages for the treatment of resistant ovarian cancer. … of resistant ovarian cancer and deserves further investigation. …
sci-hub.se 参考文章(22)
Gary Heebner, Peter Gwynne, Drug Discovery: 5 Science. ,vol. 298, pp. 1067- 1073 ,(2002)
Niravkumar R. Patel, Alok Rathi, Dmitriy Mongayt, Vladimir P. Torchilin, Reversal of multidrug resistance by co-delivery of tariquidar (XR9576) and paclitaxel using long-circulating liposomes. International Journal of Pharmaceutics. ,vol. 416, pp. 296- 299 ,(2011) , 10.1016/J.IJPHARM.2011.05.082
Kanwaldeep K. Gill, Amal Kaddoumi, Sami Nazzal, Mixed micelles of PEG(2000)-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines. European Journal of Pharmaceutical Sciences. ,vol. 46, pp. 64- 71 ,(2012) , 10.1016/J.EJPS.2012.02.010
Ajay Goel, Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal, Curcumin as “Curecumin”: From kitchen to clinic Biochemical Pharmacology. ,vol. 75, pp. 787- 809 ,(2008) , 10.1016/J.BCP.2007.08.016
Jing Cui, Bo Yu, Yu Zhao, Weiwei Zhu, Houli Li, Hongxiang Lou, Guangxi Zhai, Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems International Journal of Pharmaceutics. ,vol. 371, pp. 148- 155 ,(2009) , 10.1016/J.IJPHARM.2008.12.009
Preetha Anand, Hareesh B. Nair, Bokyung Sung, Ajaikumar B. Kunnumakkara, Vivek R. Yadav, Rajeshwar R. Tekmal, Bharat B. Aggarwal, Design of Curcumin Loaded PLGA Nanoparticles Formulation with Enhanced Cellular Uptake, and Increased Bioactivity in vitro and Superior Bioavailability in vivo Biochemical Pharmacology. ,vol. 79, pp. 330- 338 ,(2010) , 10.1016/J.BCP.2009.09.003
R SAWANT, R SAWANT, V TORCHILIN, Mixed PEG-PE/vitamin E tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: improved drug solubilization and enhanced in vitro cytotoxicity. European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 70, pp. 51- 57 ,(2008) , 10.1016/J.EJPB.2008.04.016
Alina Shapira, Yoav D. Livney, Henk J. Broxterman, Yehuda G. Assaraf, Nanomedicine for targeted cancer therapy: Towards the overcoming of drug resistance Drug Resistance Updates. ,vol. 14, pp. 150- 163 ,(2011) , 10.1016/J.DRUP.2011.01.003
Smitha V Bava, Chanickal N Sreekanth, Arun Kumar T Thulasidasan, Nikhil P Anto, Vino T Cheriyan, Vineshkumar T Puliyappadamba, Sajna G Menon, Santhosh D Ravichandran, Ruby John Anto, None, Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism. The International Journal of Biochemistry & Cell Biology. ,vol. 43, pp. 331- 341 ,(2011) , 10.1016/J.BIOCEL.2010.09.011
Chandana Mohanty, Sanjeeb K. Sahoo, The in vitro stability and in vivo pharmacokinetics of curcumin prepared as an aqueous nanoparticulate formulation Biomaterials. ,vol. 31, pp. 6597- 6611 ,(2010) , 10.1016/J.BIOMATERIALS.2010.04.062