Carcinoma of the Colon and Rectum—growth Rate

作者: S. BOLIN , E. NILSSON , R. S.J. DAHL

DOI: 10.1097/00000658-198308000-00007

关键词: Nuclear medicineRectum growthLinear growthTumor growthSurgeryCarcinomaGrowth rateRectumRadiographyMean diameterMedicine

摘要: Twenty-seven carcinomas of the colon or rectum are presented which could retrospectively be measured on radiographs at two separate occasions. The mean diameter tumors first and second investigations was 35 mm (10-90 mm) 65 (30-110 mm), respectively, median interval between these examinations 11 months (4-91 months). linear growth rate 0.083 mm/day (0.008-0.262 mm/day). time for doubling tumor volume 130 days (53-1570 days), assuming a three-dimensional pattern growth. A significant correlation poor differentiation high (greater than equal to 0.1 mm/day) found. It is suggested that observed in this investigation comparison with some previous studies may due large size and, hence, their great risk being malignant already examination.

参考文章(12)
Basil Morson, President's address. The polyp-cancer sequence in the large bowel. Journal of the Royal Society of Medicine. ,vol. 67, pp. 451- 457 ,(1974) , 10.1177/00359157740676P115
John P. Welch, Multiple colorectal tumors. An appraisal of natural history and therapeutic options. American Journal of Surgery. ,vol. 142, pp. 274- 280 ,(1981) , 10.1016/0002-9610(81)90292-0
G G Steel, L F Lamerton, The growth rate of human tumours. British Journal of Cancer. ,vol. 20, pp. 74- 86 ,(1966) , 10.1038/BJC.1966.9
T. Muto, H. J. R. Bussey, B. C. Morson, The evolution of cancer of the colon and rectum. Cancer. ,vol. 36, pp. 2251- 2270 ,(1975) , 10.1002/CNCR.2820360944
R. J. Heald, H. J. R. Bussey, Clinical experiences at St. Mark’s Hospital with multiple synchronous cancers of the colon and rectum Diseases of The Colon & Rectum. ,vol. 18, pp. 6- 10 ,(1975) , 10.1007/BF02587230
Keith R. Burnett, Edward I. Greenbaum, Rapidly growing carcinoma of the colon Diseases of the Colon & Rectum. ,vol. 24, pp. 282- 286 ,(1981) , 10.1007/BF02641878
N. Gabrielsson, S. Granqvist, H. Ohlsén, P. Sundelin, Malignancy of colonic polyps. Diagnosis and management. Acta radiologica: diagnosis. ,vol. 19, pp. 479- 495 ,(1978) , 10.1177/028418517801900309
Silverberg Sg, Focally malignant adenomatous polyps of the colon and rectum. Surgery gynecology & obstetrics. ,vol. 131, pp. 103- 114 ,(1970)