Fine needle aspiration cytology of papillary lesions of the breast - how accurate is the diagnosis?

作者: GMK Tse , Tony KF Ma , Philip CW Lui , David CH Ng , AMC Yu

DOI: 10.1136/JCP.2008.057489

关键词: AtypiaLesionDifferential diagnosisFine needle aspiration cytologyMammary glandPapillomaPathologyAnatomical pathologyMedicineCytology

摘要: Aim: Cytological diagnosis of mammary papillary lesions is difficult. We reviewed the previous cytology 23 papillomas and 11 carcinomas specific cytological features that may assist in differentiating these entities. Methods: The preparations were for (i) overall cellularity; (ii) epithelial cell ball devoid fibrovascular cores; (iii) single cells; (iv) fragments their morphology. Results: diagnostic accuracy was 59%, atypical rate 24%, error (combined false positive negative) 17%. For cellularity, six, 14 three cases two carcinoma showed low, moderate to high cellularity respectively. Cell balls present mild number 20 ten carcinomas. background cells absent, low or numbers seven, six three, five Papillary small, large quantities nine, four, eight one There no demonstrable quantitative difference between papilloma all parameters. Qualitatively, higher degree atypia carcinoma, more elaborate slender. Summary: shows significant with overlapping features. Cellular long slender papillae ramifying edges favours carcinoma.

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