Fuchs’ corneal dystrophy

摘要: Fuchs’ corneal dystrophy (FCD) is a progressive, hereditary disease of the cornea first described century ago by Austrian ophthalmologist Ernst Fuchs. Patients often present in fifth to sixth decade life with blurry morning vision that increases duration as progresses. Primarily condition posterior cornea, characteristic features include formation focal excrescences Descemet membrane termed ‘guttae’, loss endothelial cell density and end-stage manifested edema epithelial bullae. Recent advances our understanding genetic pathophysiological mechanisms disease, well application new imaging modalities less invasive surgical procedures, opportunities for improved outcomes among patients FCD.