摘要: Es darf angenommen werden, das die befruchtete Eizelle gesamte Information besitzt, zur Entstehung und Entwicklung des Organismus notwendig ist. Der schrittweise Ausdruck (Expression) der in DNA Zygote vorhandenen geschieht offenbar einer zeitlich genau abgestimmten Reihenfolge, durch eine grose Zahl von Regulationsmechanismen kontrolliert zu sein scheint. Die biochemischen Hintergrunde dieses Geschehens konnten bisher weiten Teilen nicht geklart werden. Man ist daher vorlaufig auf Modellvorstellungen angewiesen.
springer.com
sci-hub.st 参考文章(89)
W Bersch, B Chuaqui, The periods of determination of cardiac malformations. Virchows Archiv. A, Pathology. Pathologische Anatomie. ,vol. 356, pp. 95- 110 ,(1972) , 10.1007/BF00549282
C.J. D'Amato, S.P. Hicks, EFFECTS OF IONIZING RADIATIONS ON MAMMALIAN DEVELOPMENT. pp 195-250 of Advances in Teratology. Woollam, D. H. M. (ed.). London, Logos Press, 1966.. ,(1967)
M. Ryser, R. Fisher, R. L. Naeye, P. Whalen, Cardiac and other abnormalities in the sudden infant death syndrome. American Journal of Pathology. ,vol. 82, pp. 1- 8 ,(1976)
Opendra Narayan, Henry F. McFarland, Richard T. Johnson, Effects of viral infection on nervous system development. II. Attempts to modify bluetongue-virus-induced malformations with cyclophosphamide and antithymocyte serum. American Journal of Pathology. ,vol. 68, pp. 15- 22 ,(1972)
Lauri Saxén, Defective Regulatory Mechanisms in Teratogenesis Springer, Dordrecht. pp. 80- 86 ,(1970) , 10.1007/978-94-011-6621-8_8
Lytt I. Gardner, Endocrine and genetic diseases of childhood Saunders. ,(1969)
Olga Greengard, Effects of hormones on development of fetal enzymes. Clinical Pharmacology & Therapeutics. ,vol. 14, pp. 721- 726 ,(1973) , 10.1002/CPT1973144PART2721
Opendra Narayan, Richard T. Johnson, Effects of viral infection on nervous system development. I. Pathogenesis of bluetongue virus infection in mice. American Journal of Pathology. ,vol. 68, pp. 1- 14 ,(1972)
A Ornoy, K Crone, G Altshuler, Pathological features of the placenta in fetal death. Archives of Pathology & Laboratory Medicine. ,vol. 100, pp. 367- 371 ,(1976)
Richard L. Naeye, William A. Blanc, Fetal renal structure and the genesis of amniotic fluid disorders. American Journal of Pathology. ,vol. 67, pp. 95- 108 ,(1972)