Adrenergic alpha 1 and alpha 2 binding sites are present in bovine retinal blood vessels.

作者: G Ferrari-Dileo , D R Anderson , B A Forster

DOI:

关键词: RetinaDopamineDissociation constantAdrenergicBinding siteRetinalBiophysicsEndocrinologyAlpha-2 adrenergic receptorInternal medicineNorepinephrine (medication)Chemistry

摘要: Bovine retinal vessels have sites that specifically bind 3H-p-aminoclonidine (3H-PAC) with an apparent dissociation constant of 0.12 nM and a capacity binding 0.15 pmol/g. In addition, these 3H-prazosin bearing 5 To understand the implications for retina-optic nerve vascular physiology pathophysiology, studies exact location sites, bioavailability adrenergic agonists, physiological responses to receptor stimulation in both normal pathological states are required. The neural elements retina also 3H-PAC 0.38 larger quantities (6.7 pmol/g tissue) than elements. There lower amount fraction (3 2.4 nM. These presumably related use norepinephrine dopamine as neurotransmitters by neurons.

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