作者: Donatella Zappulla
DOI: 10.1111/J.1559-4572.2008.07263.X
关键词: Proinflammatory cytokine 、 Inflammation 、 Methemoglobin 、 Peroxynitrite 、 Red blood cell 、 Nitric oxide 、 Immunology 、 Systemic inflammation 、 Medicine 、 Phospholipid scrambling
摘要: In the Western world, the prevalence of the metabolic syndrome is increasing exponentially. Chronic subacute inflammation characterizes the syndrome, suggesting that inflammation might be a common denominator that links obesity to its pathologic sequelae. Potential mechanisms for the activation of inflammation include current air pollution inhalation and/or excess food intake. Both of these environmental factors have, in fact, been shown to promote oxidation followed by the release of proinflammatory cytokines. Potential sources of systemic …