Calcium and magnesium ATPase activities in women with varying BMIs.
作者： Jennifer A. Nasser , Sami A. Hashim , Paul A. Lachance
DOI: 10.1038/OBY.2004.229
关键词: Medical history 、 Calcium in biology 、 Calcium 、 Family history 、 Obesity 、 Adult women 、 Medicine 、 Internal medicine 、 Magnesium-ATPase 、 Whole blood 、 Endocrinology
摘要: Objective: Intracellular calcium (Ca) is increased in obese humans, and magnesium (Mg)-ATPase activity monosodium glutamate-induced rats. The aims of this study were to test the hypotheses that Ca-ATPase negatively correlated with BMI, Mg-ATPase positively BMI women. Research Methods Procedures: Thirty healthy adult women, BMIs 20 40, donated a single sample whole blood interviewed as medical history family obesity. Erythrocyte membranes isolated assayed for Mg-ATPase. Weight height self-reported. Regression analysis was used determine relationship between enzyme activity. Family obesity served covariant. Results: increasing (r = − 0.38, p 0.02). remained valid after controlling −0.36, 0.03). There positive correlation 0.42, 0.024), 0.41, 0.03). Discussion: decreases increases. Decreased ATPase may contribute intracellular calcium, previously reported persons. Further studies are needed whether drop can serve marker development
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