Injection sclerotherapy for varicose veins

摘要: Background Injection sclerotherapy for varicose veins has been used widely since 1963, following popularisation of the technique by Fegan. The treatment aims to obliterate lumen or thread veins, however, there is limited evidence regarding its efficacy. Objectives To determine whether effective in terms symptomatic improvement and cosmetic appearance; an acceptable complication rate; define rates vein recurrence sclerotherapy. Search strategy Publications describing randomised controlled trials (RCTs) injection (excluding comparisons with surgery) were sought through EMBASE MEDLINE (from inception March 2001) hand-searching relevant journals, using search described Cochrane Peripheral Vascular Diseases Review Group. Bibliographies papers identified examined further RCTs. Manufacturers sclerosants contacted trial information. Selection criteria RCTs versus graduated compression stockings 'observation', comparing different sclerosants, doses post-compression bandaging techniques on patients and/or considered inclusion review. Data collection analysis Ten studies included analysis. These compared: sodium tetradecyl sulphate (STD) alternative sclerosant; sclerosant without local anaesthetic; application Molefoam Sorbo pads sites; elastic conventional bandaging; short-term standard bandaging. abstracted both authors. Main results No compared other non-surgical treatments. Two STD found no significant differences outcome rates. Adding anaesthetic reduced pain from (one study) but had effects. Comparison pad pressure dressings difference erythema (redness) successful sclerosis. degree duration effect rates, appearance improvement. Increased prevented slipping caused increased discomfort, as did increasing compression. Reviewer's conclusions Evidence suggests that type sclerosant, dressing, length have efficacy veins. This supports current place modern clinical practice, which usually recurrent surgery, A comparison surgery would be valuable.