Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance
作者： J. Zhou , J. Wulfkuhle , H. Zhang , P. Gu , Y. Yang
关键词: Cell biology 、 Cancer stem cell 、 PI3K/AKT/mTOR pathway 、 Cancer research 、 PTEN 、 Cell culture 、 Tensin 、 Cellular differentiation 、 Cell cycle 、 Biology 、 Signal transduction
摘要: … When PTEN was knocked down by a validated shRNA (22), expression … PTEN also plays a role in SP phenotype regulation, we analyzed the SP fraction within PTEN knockdown MCF7 …
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