On the “Zero of Potential of the Electric Field Produced by the Heart Beat”. A Machine Capable of Estimating this Underlying Persistent Error in Electrocardiography

摘要: Modern electrocardiography (ECG) uses a constructed reference potential for the majority of leads. This potential, named after its inventor as Wilson central terminal, is assumed to have negligible value and be stationary during cardiac cycle. However, problem variability cycle has been known almost since inception 12-lead electrocardiography. Due cumbersomeness measurement system required fully appreciate these variations, this topic received scant research attention last 60 years. Taking advantage modern electronic amplifiers’ capability detect small voltages, drawing only femtoamperes from physiological equivalent signal sources right-leg connection availability, we developed complete device that, aside eight independent signals standard ECG, allows direct recording terminal components. In paper, present details circuit together with initial clinical evaluation. For trial, recorded data 44 volunteer patients at Campbelltown Hospital (Campbelltown, Australia) found that amplitude, foreseen by Frank others in 1950s, not negligible, amplitude relation lead II is, on average, 51.2%, thus it may clinically relevant.