Predictors of recurrence in high-grade cervical lesions and a plan of management.

摘要: Abstract Precis Positive endocervical margins are an important predictor of recurrence in high-grade cervical lesions, and though they do not always warrant retreatment, closer surveillance is recommended. Objective To identify predictors persistence dysplasia to determine appropriate follow-up. Design: prospective pilot study. Setting: Gynaecological surgical center. Population Three hundred fifty-two patients were treated between 1999 2002 for lesions. Methods According the accessibility transformation zone degree dysplasia, either by conization or loop electrosurgical excision procedure (LEEP). Follow-up comprised colposcopy Pap-smear screening 4–6 months after treatment as well high-risk human papillomavirus (HR-HPV) testing before treatment. Main outcome measures underscore propose a flowchart both management Results Of 352 patients, 37 (10.5%) had true 6 initial (1.7%) persistent Overall, 43 (12.2%) considered having recurrent disease. Patients followed up 5 years with mean 73 months. The most was positive HR-HPV test at postoperatively (odds ratio 38.8, 95% confidence interval 14.09, 107.05). second significant third pre-treatment HPV typing. A post-treatment more influence on risk than Conclusion In agreement recent findings, our study supports usefulness follow-up especially when positive.