Primordial odontogenic tumor occurred in the maxilla with unique calcifications and its crucial points for differential diagnosis.

摘要: Primordial odontogenic tumor (POT) is a newly classified, mixed epithelial and mesenchymal tumor, with only 17 reported cases to date. Herein, we report case of POT that occurred in the right maxilla 10-year-old boy reveal unique features comparison those previously reported. Radiologically, lesion presented as well-defined, unilocular radiolucency notable radiopaque foci on periphery. Microscopically, was mainly composed dental papilla-like myxoid fibrous connective tissue, largely surrounded by non-keratinized squamous epithelium numerous calcified particles, partly enclosed inner enamel epithelium-like columnar cells organ-like structures accompanied cuboidal and/or stellate reticulum-like cells. Immunohistochemically, tested positive for cytokeratin 14 19. Moreover, amelogenin ameloblastin, matrix proteins relating formation, were covering epithelium. The enucleated whole, no recurrence recorded thereafter. Although presence particles unique, diagnosed this based above-described features. Furthermore, emphasize importance differential diagnosis other tumors resemble corresponding tooth germ components.