Clam-inspired nanoparticle immobilization method using adhesive tape as microchip substrate
作者： Xiaowen Huang , Yujiao Zhu , Xuming Zhang , Zhiyong Bao , Dang Yuan Lei
DOI: 10.1016/J.SNB.2015.08.069
关键词: Microfabrication 、 Nanotechnology 、 Biochip 、 Microfluidics 、 Materials science 、 Biomimetics 、 Substrate (printing) 、 Adhesive 、 Nanorod 、 Nanoparticle
摘要: Abstract Immobilization of the suspended nanoparticles is essential for many microfluidic applications. This work reports a novel biomimetic method to immobilize by using common adhesive tape as substrate chip. It mimics clams’ feeding system that utilizes mucus (i.e., sticky fluid) capture small phytoplankton particles in water. proves experimentally this has better immobilization effect and stronger shear stress resistance than traditional methods hard glass substrates. Moreover, we have applied Au nanorods detection R6G various concentrations surface-enhanced Raman scattering (SERS) effect. enjoys several major merits: can seal structure easily, avoiding bonding process; easy environmental friendly, without need expensive reagents or complex processes; allows flexibility chips; be stripped off off-chip replaced easily reuse structures. With these, may find potential applications sensing, biocatalysis biosynthesis microchips.
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