Human embryonic stem cells: A potential source for cellular therapy
作者： Sharon Gerecht-Nir , Joseph Itskovitz-Eldor
DOI: 10.1111/J.1600-6135.2004.0345.X
关键词: Clinical uses of mesenchymal stem cells 、 Stem cell 、 Adult stem cell 、 Cancer research 、 Amniotic epithelial cells 、 Embryonic stem cell 、 Stem cell transplantation for articular cartilage repair 、 Medicine 、 Endothelial stem cell 、 Cell therapy 、 Pathology
摘要: Many degenerative human diseases reflect damage to cells that are not normally repaired or replaced, such as diabetes, Parkinson's disease, hepatic failure and congestive heart failure. Preliminary studies in animals humans have suggested these may be treatable by transplantation of healthy cells. Such obtained vitro culture embryonic stem cells, which capable differentiating into many cell types. This review discusses applicative approaches for the derivation, maintenance safety (hES) well ethical concerns surrounding their possible source cellular therapy. hES offer broad application therapy; however, this specifically emphasizes on cardiovascular repair, generation characterization cell-derived cardiomyocytes, vascular progenitors differentiation derivatives.
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