Cardioprotective repair through stem cell-based cardiopoiesis.

摘要: Ischemic heart disease continues to progress at pandemic levels despite current preventive and therapeutic interventions. Recent advances in stem cell biology have provided the impetus for a paradigm shift treatment options, potentially transforming palliative care into curative therapy. Although delivery of cells clinical trials has resulted modest functional improvement myocardial performance setting infarction, ongoing efforts bench bedside are taking place increase propensity engraftment homing diseased myocardium. The newest opportunity arisen with guided execute cardiac program. Here, we examine recent application genomic proteomic technology decipher process cardiopoiesis recruit cardiopoietic cardioprotection safe repair.