The Antinociceptive and Antihyperalgesic Effects of Topical Propofol on Dorsal Horn Neurons in the Rat

作者: Kenichi Takechi , Mirela Iodi Carstens , Amanda H. Klein , E. Carstens

DOI: 10.1213/ANE.0B013E31827F560D

关键词: AnesthesiaAnestheticPropofolDorsumAnalgesicHyperalgesiaMedicinePosterior Horn CellNociceptionPharmacologyThreshold of painAnesthesiology and Pain Medicine

摘要: BACKGROUND:Propofol (2,6-diisopropylphenol) is an IV anesthetic used for general anesthesia. Recent evidence suggests that propofol-anesthetized patients experience less postoperative pain, and propofol has analgesic properties when applied topically. We presently investigated the antinocicepti

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