Developmental Regulation and In Vitro Culture Effects on Expression of DNA Repair and Cell Cycle Checkpoint Control Genes in Rhesus Monkey Oocytes and Embryos

作者: Ping Zheng , R. Dee Schramm , Keith E. Latham

DOI: 10.1095/BIOLREPROD.104.039073

关键词: G2-M DNA damage checkpointCell cycleDNA damageGeneticsCell biologyCHEK1GeneDNA replicationDNA repairBiologyDNA

摘要: DNA repair is essential for maintaining genomic integrity, and may be required in the early embryo to correct damage inherited via the gametes, damage that arises during DNA …

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