Effect of pregnancy on uterine and carotid artery response to norepinephrine, epinephrine, and phenylephrine in vessels with documented functional endothelium.
作者： Carl P. Weiner , Ernest Martinez , David H. Chestnut , Abdi Ghodsi
DOI: 10.1016/0002-9378(89)90934-4
关键词: Endothelium 、 Norepinephrine (medication) 、 Medicine 、 Epinephrine 、 Cardiology 、 Internal medicine 、 Artery 、 Anesthesia 、 Circulatory system 、 Uterine artery 、 Blood vessel 、 Phenylephrine
摘要: The effect of pregnancy on arterial sensitivity to vasoconstrictors is controversial. Some the controversy may reflect methodologic differences. Vessel reactivity in vitro altered by both tension placed segment and presence or absence functional endothelium. We investigated guinea pig uterine carotid arteries norepinephrine, epinephrine, phenylephrine. Each vessel was stretched optimal point along its length-tension curve, endothelium documented acetylcholine-stimulated relaxation. A significant dose-response relationship observed each for agent (each p
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