Cryptococcal meningitis in patients with autoimmune hemolytic anemia.
作者： YaLi Yang , Junjun Sang , Weihua Pan , Lin Du , Wanqing Liao
DOI: 10.1007/S11046-014-9741-9
关键词: Immunology 、 Autoimmune hemolytic anemia 、 Anemia 、 Amphotericin B 、 Internal medicine 、 Gastroenterology 、 Medicine 、 Cryptococcus 、 Splenectomy 、 Prednisone 、 Nausea 、 Cryptococcosis
摘要: To summarize the epidemiology, clinical features, treatment, and outcome of cryptococcal meningitis (CM) in autoimmune hemolytic anemia (AIHA) patients to provide a reference for prevention control AIHA complicated with CM, we evaluated five cases CM treated our hospital from 2003 2013 eight related foreign cases. All isolates were Cryptococcus neoformans var. grubii grouped into VNI genotype serotype A. The features exhibit significant features. Headache, nausea, fever are common symptoms CM. early manifestations lack specificity, which may lead delayed diagnosis treatment. Long-term use prednisone (≥15 mg day−1), poor anemia, splenectomy risk factors infection. combination intravenous amphotericin B oral 5-fluorocytosine remains preferred treatment
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sci-hub.se 参考文章(26)
Chen Yuchong, Chen Jianghan, Wen Hai, Gu Julin, Lumbar puncture drainage with intrathecal injection of amphotericin B for control of cryptococcal meningitis. Mycoses. ,vol. 54, ,(2011) , 10.1111/J.1439-0507.2009.01847.X
CRYPTOCOCCUS MENINGITIS IN A CASE OF CONGENITAL HEMOLYTIC ANEMIA Annals of Internal Medicine. ,vol. 44, pp. 1015- 1019 ,(1956) , 10.7326/0003-4819-44-5-1015
Chadi A. Hage, Karen L. Wood, Helen T. Winer-Muram, Stephen J. Wilson, George Sarosi, Kenneth S. Knox, Pulmonary Cryptococcosis After Initiation of Anti-Tumor Necrosis Factor-α Therapy Chest. ,vol. 124, pp. 2395- 2397 ,(2003) , 10.1378/CHEST.124.6.2395
Q. T. Kong, W. Q. Zhou, J. Feng, H. Sang, D. Q. Deng, Z. Wang, J. Li, Q. L. Shi, B. Wu, W. D. Liu, Isolated skull cryptococcosis in an immunocompetent patient. Mycopathologia. ,vol. 175, pp. 187- 191 ,(2013) , 10.1007/S11046-012-9609-9
Z. Qazzafi, D. Thiruchunapalli, D. Birkenhead, D. Bell, J.A.T. Sandoe, Invasive Cryptococcus neoformans infection in an asplenic patient Journal of Infection. ,vol. 55, pp. 566- 568 ,(2007) , 10.1016/J.JINF.2007.08.005
Chaitanya Nigam, Rupam Gahlot, Vikas Kumar, Jaya Chakravarty, Ragini Tilak, Central Nervous System Cryptococcosis among a Cohort of HIV Infected Patients from a University Hospital of North India Journal of clinical and diagnostic research : JCDR. ,vol. 6, pp. 1385- 1387 ,(2012) , 10.7860/JCDR/2012/4158.2365
D.S. Nath, R. Kandaswamy, R. Gruessner, D.E.R. Sutherland, D.L. Dunn, A. Humar, Fungal infections in transplant recipients receiving alemtuzumab. International Congress of the Transplantation Society. ,vol. 37, pp. 934- 936 ,(2005) , 10.1016/J.TRANSPROCEED.2005.01.054
Monica Pau, Cesarina Lallai, Natalia Aste, Nicola Aste, Laura Atzori, Primary cutaneous cryptococcosis in an immunocompetent host. Mycoses. ,vol. 53, pp. 256- 258 ,(2010) , 10.1111/J.1439-0507.2009.01707.X
Weihua Pan, Kantarawee Khayhan, Ferry Hagen, Retno Wahyuningsih, Arunaloke Chakrabarti, Anuradha Chowdhary, Reiko Ikeda, Saad J. Taj-Aldeen, Ziauddin Khan, Darma Imran, Ridhawati Sjam, Pojana Sriburee, Wanqing Liao, Kunyaluk Chaicumpar, Natnicha Ingviya, Johan W. Mouton, Ilse Curfs-Breuker, Teun Boekhout, Jacques F. Meis, Corné H. W. Klaassen, Resistance of Asian Cryptococcus neoformans Serotype A Is Confined to Few Microsatellite Genotypes PLoS ONE. ,vol. 7, pp. e32868- ,(2012) , 10.1371/JOURNAL.PONE.0032868
Alexandra F. Gazzoni, Javier Capilla, Emilio Mayayo, Josep Guarro, Efficacy of intrathecal administration of liposomal amphotericin B combined with voriconazole in a murine model of cryptococcal meningitis. International Journal of Antimicrobial Agents. ,vol. 39, pp. 223- 227 ,(2012) , 10.1016/J.IJANTIMICAG.2011.10.014