Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.

作者: Peter C. Preusch , David Siegel , David Ross , Neil W. Gibson

DOI:

关键词: Cell cultureCytosolDicoumarolGenotoxicityMitomycin CDNA damageBiologyPorfiromycinBiochemistryCytotoxicity

摘要: … Micrococcus luteus DNA after chemical reduction of mitomycin C in vitro and was also isolated from rat hepatic DNA after injection of mitomycin C (25). Mitomycin C-induced DNA cross-…

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