The association between length of post‐kidney transplant hospitalization and long‐term graft and recipient survival

作者: Shih-jui Lin , James K. Koford , Bradley C. Baird , Arsalan N. Habib , Ilya Reznik

DOI: 10.1111/J.1399-0012.2005.00476.X

关键词: Statistical significanceSurvival analysisAdverse effectProportional hazards modelSurgeryTransplantationKidney transplantMedicineUrinary systemCohort

摘要: : Background: There has been a general trend towards shortened length of post-kidney transplant hospitalization (LOH). The decision regarding patients's discharge from the hospital theoretically may be based on several factors, including, but not limited to, patient well being, insurance status, family situation and other, mostly socio-economic as opposed to hard medical evidence. However, appropriate LOH in kidney recipients is studied long-term outcomes. Methods: This study retrospectively analysed association between graft recipient survival United States Renal Data System dataset. In total, 100 762 patients who underwent during 1995–2002 were included. Kaplan–Meier analysis Cox models applied whole cohort sub-groups stratified by presence delayed function, comorbidity index donor type (deceased or living). Results: survival, both short ( 5 d) showed significant adverse effect (p<0.01) times. long (≥2 wk) also effects (p<0.001) (<4 d) did reach statistical significance, although it was still associated with survival. These observations consistent across type. Conclusion: Clinical considerations should used make time discharge. Based this study, shorter than four d potentially harmful

参考文章(21)
Scantlebury Vp, Doyle Hr, Gritsch Ha, Vivas C, McCauley J, Jordan Ml, Simmons Rl, Fung Jj, Fenton R, Starzl Te, Fox-Hawranko L, Redman C, Johnson Lb, Keefer-Wolf K, Painter L, Hakala Tr, Shapiro R, Reducing the length of stay after kidney transplantation--the intensive outpatient unit. Clinical Transplantation. ,vol. 12, pp. 482- 485 ,(1998)
Barbara A. Elick, John S. Najarian, Kristen J. Gillingham, David L. Dunn, William D. Payne, David E.R. Sutherland, Rainer W.G. Gruessner, Arthur J. Matas, Risk factors for prolonged hospitalization after kidney transplants. Clinical Transplantation. ,vol. 11, pp. 259- 264 ,(1997)
John C. Bucuvalas, Lan Zeng, Ravinder Anand, , Predictors of length of stay for pediatric liver transplant recipients Liver Transplantation. ,vol. 10, pp. 1011- 1017 ,(2004) , 10.1002/LT.20203
Mary E. Charlson, Peter Pompei, Kathy L. Ales, C.Ronald MacKenzie, A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation☆ Journal of Chronic Diseases. ,vol. 40, pp. 373- 383 ,(1987) , 10.1016/0021-9681(87)90171-8
Nancy Noedel, Joan Osterloh, Jenny Brannan, Mary Haselhorst, Lisa Ramage, Donna Lambrechts, Critical pathways as an effective tool to reduce cardiac transplantation hospitalization and charges. Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization. ,vol. 6, pp. 14- 19 ,(1996) , 10.7182/PRTR.1.6.1.0L68284560715857
Jeremy Holtzman, Treva Bjerke, Robert Kane, The effects of clinical pathways for renal transplant on patient outcomes and length of stay. Medical Care. ,vol. 36, pp. 826- 834 ,(1998) , 10.1097/00005650-199806000-00006
Christopher P Johnson, Evelyn M Kuhn, Sundaram Hariharan, Arthur J Hartz, Allan M Roza, Mark B Adams, PRE-TRANSPLANT IDENTIFICATION OF RISK FACTORS THAT ADVERSELY AFFECT LENGTH OF STAY AND CHARGES FOR RENAL TRANSPLANTATION Clinical Transplantation. ,vol. 13, pp. 168- 175 ,(1999) , 10.1034/J.1399-0012.1999.130203.X
Sundaram Hariharan, Long-term kidney transplant survival. American Journal of Kidney Diseases. ,vol. 38, ,(2001) , 10.1053/AJKD.2001.28925
Linda Fried, Judith Bernardini, Beth Piraino, Charlson comorbidity index as a predictor of outcomes in incident peritoneal dialysis patients. American Journal of Kidney Diseases. ,vol. 37, pp. 337- 342 ,(2001) , 10.1053/AJKD.2001.21300