Cancer breakthrough pain characteristics and responses to treatment at a VA medical center.

摘要: The purpose of this study is to analyze cancer breakthrough pain (BP) characteristics and how BP responds conventional management. Seventy-four patients with worst severity >or=4 out 10 completed the Brief Pain Inventory (BPI), Memorial Symptom Assessment Scale-Short Form, Functional Cancer Therapy Breakthrough Questionnaires (BPQ) at an initial interview. Agency for Health Care Policy Research (AHCPR) management guidelines were followed. syndromes morphine equivalent daily dose (MEDD) orally determined. One-week follow-up assessments obtained in 66 BPI BPQ. similar both time points. On day 1, 52 (70%) had BP, was unpredictable 30 (58%). median 3 min. Patients significantly higher (P<0.001). At week MEDD doubled from 60 120 mg orally, number who received adjuvant analgesics 31.1% (23 patients) on 1 62.2% (41 patients). 21 (32%) remained without classified as responders 24 (36%) non-responders. mean relief all three subgroups, i.e. around 80%. Compared responders, non-responders (P<0.0001), average (P<0.004), interference parameters shorter severity. confirmed applicability BPQ US veteran population, that following AHCPR effective a group related BP. Underlying location may influence response treatment. bone located spine, back, pelvis be risk resistant