Establishment and pathophysiological characterization of type 2 diabetic mouse model produced by streptozotocin and nicotinamide.

作者: Tomonori Nakamura , Tomoko Terajima , Taeko Ogata , Koichi Ueno , Naotake Hashimoto

DOI: 10.1248/BPB.29.1167

关键词: NicotinamideEndocrinologyInternal medicineHyperlipidemiaInsulinGlucose tolerance testInsulin resistanceType 2 diabetesDiabetes mellitusMedicineStreptozotocin

摘要: … mouse model is useful for searching drugs that are beneficial to treatment of the non-obese type 2 diabetes. … if the optimal protocol procedures induce pathophysiological features of a …

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