Tumor Receptor Imaging: Proceedings of the National Cancer Institute Workshop, Review of Current work, and Prospective for Further Investigations

作者: J A Katzenellenbogen , K A Krohn , R A Hawkins , B A Siegel , S M Larson

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关键词: Breast cancerPositron emission tomographyNeuroendocrine tumorsOncologyEpidermal growth factor receptorInternal medicineTumor Cell BiologyCancerEstrogen receptorPathologyMedicineEmission computed tomography

摘要: In February 1994, the National Cancer Institute held a workshop to evaluate current and future role of emission tomographic imaging methods, positron tomography single-photon computed tomography, in improving accuracy cancer diagnosis effectiveness treatment elucidating basic aspects human biology. Reviews covered many receptor transport systems for hormones growth factors, as well metabolic changes important cancer, topical presentations reviewed status receptor-based most well-characterized systems: somatostatin neuroendocrine tumors, estrogen breast epidermal factor tumor imaging. A critical analysis was made research new directions development use receptor-imaging methods oncology. each area, recommendations were further investigation, where emerging understanding cell biology defined molecular targets might be combined with radiopharmaceutical design evaluation, develop approaches issues diagnosis, staging, through

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