Supercomputer analysis of purine and pyrimidine metabolism leading to DNA synthesis.

作者: F. Heinmets

DOI: 10.1007/BF02797274

关键词: Pyrimidine metabolismDNA synthesisPurine metabolismSupercomputerStereochemistryNucleotideBiological systemDifferential equationPurineBiologyPyrimidine

摘要: A model-system is established to analyze purine and pyrimidine metabolism leading DNA synthesis. The principal aim explore the flow regulation of terminal deoxynucleoside triophosphates (dNTPs) in various input parametric conditions. series equations are established, which subsequently converted differential equations. These programmed (Fortran) analyzed on a Cray X-MP/48 supercomputer. pool concentrations presented as function time conditions pertinent parameters system modified. formulated by 100

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